Which means ... yep, the rout is on.
The good news for Jacksonville is that even though this is considered a home game it's thousands of miles away from Florida. The Jags this season have exactly 11 points at home, with their next touchdown there their first. Bad, huh? It gets worse. They're playing a team beginning to find itself -- a league heavyweight that has outscored opponents by an average of 20 points per during its four-game winning streak.
Bottom line: Prince George's baptism this week offered more suspense than this game.
Something to consider: Not only have the 49ers won four straight, they scored over 30 points in each of those games.
FIVE GUYS IT'S GOOD TO BE IN WEEK 8
1. Detroit defensive tackle Nick Fairley. In his past six games at home he has 3.5 sacks, two forced fumbles and two fumble recoveries.
2. Kansas City running back Jamaal Charles. He averages 122.7 yards rushing per game in three career starts vs. Cleveland.
3. New Orleans quarterback Drew Brees. Since 2011, he's 15-4 at home with 64 touchdowns, 16 interceptions and a passer rating of 113.5.
4. Green Bay quarterback Aaron Rodgers. He has a 116.4 passer rating in his regular-season career vs. Minnesota, with 24 touchdown passes and four interceptions. According to the Elias Sports Bureau, Rodgers' passer rating is the highest in NFL history for a quarterback vs. a single opponent (minimum 250 attempts). Rodgers has a passer rating of at least 130.0 in four of his last five starts vs. the Vikings and had ratings of 140 or better in three straight against them.
5. Denver quarterback Peyton Manning. He's 11-1 at home, with 38 touchdowns, 4 interceptions and a 120.0 passer rating. Plus, he faces the NFL's worst-ranked defense.
BELIEVE IT ... OR DON'T
1. Since 1990, 32 teams had losing records through the first seven games, yet went on to reach the playoffs. In fact, Cincinnati and Washington did it last season.
2. The Pittsburgh Steelers have won nine of their last 10 in October.
3. Detroit is 4-0 this season when forcing at least one turnover.
4. The New Orleans Saints have won their last four games immediately following byes.
5. Green Bay is 20-6 in Sunday night games, the best winning percentage in the NFL. The Packers have won seven of their last nine Sunday -night games and are 8-4 on Sunday nights under coach Mike McCarthy.
6. Cincinnati's Andy Dalton is the most accurate active passer inside the red zone, with 40 career touchdowns and one interception. Green Bay's Aaron Rodgers is second, with 118 touchdowns and three interceptions (a 39.3:1 ratio) and Tom Brady is third with 238 touchdowns and 12 pickoffs (a 19.8:1 ratio).
7. The Chiefs' Jamaal Charles has at least 100 yards from scrimmage and a touchdown in each of his first seven games, joining Hall of Famer O.J. Simpson as the only NFL players to accomplish that feat.
8. Eleven teams average 25 or more points per game, on pace to be the most in NFL history.
9. With 30 points this weekend, Denver becomes the third team in NFL history to score at least that many in each of its first eight starts. The 2007 New England Patriots and 2000 St. Louis Rams are the others.
10. If Kansas City holds Cleveland to no more than 17 points, the Chiefs become the fourth team since 1970 to start the season by allowing no more than 17 in each of its first eight games. The 1977 Atlanta Falcons were the last to do it.
TEN NUMBERS THAT MAY MEAN SOMETHING
4-0 -- Andy Reid vs. Cleveland
6 -- Receiving tandems with two players are on pace to finish with 1,000 yards each
7 -- Games this season where Seattle has two or more takeaways