The startling discovery that three women had been held captive for a decade inside a Cleveland home has answered key questions from their families and raised a slew of others.
Here are some of the most pressing:
What was life like for the victims?
Ropes and chains taken as evidence from the modest, two-story home on Seymour Avenue where the women were held were used to restrain the women, Police Chief Michael McGrath told NBC's "Today." "We have confirmation that they were bound," he said.
But Public Safety Director Martin Flask said it was not clear what they were used for.
Victor Perez, chief assistant prosecutor for Cleveland, announced Wednesday that charges against Ariel Castro include four counts of kidnapping -- one each for Georgina "Gina" DeJesus, Michelle Knight, Amanda Berry and a 6-year-old girl who was born to Berry in captivity.
Those charges also address the question of whether the women were sexually abused. Castro, 52, faces three counts of rape, Perez said, adding that a grand jury could later indict him on additional charges.
Two of Castro's brothers who also were arrested after the women's escape Monday evening will not be charged, according to the prosecutor. Perez said "there is no evidence these two individuals had any involvement."
As to the victims, two of them returned home Wednesday. But they have not made public statements as they seek to be reacquainted with family and friends.
The interior of their prison was unremarkable, according to Tito DeJesus. The sometime bandmate of the homeowner, suspect Ariel Castro, said he entered the house about two years ago to to help deliver a washer and dryer and saw "a normal environment."
"It didn't seem to be a place where women were being held against their will," he said. "Of course, mind you, I didn't go throughout the entire house. I was just at the beginning of the house, in the living room, but it seemed normal."
The one-bathroom house has a living area of 1,436 square feet, with a living room inside the front door, a dining room and a kitchen on the ground floor, according to Cuyahoga County records.
The four bedrooms are all on the second floor. Because the ground is sandy and loose in the area, basements in the area tend to be smaller than the footprints of the houses above, which are usually damp and cold in the winter.
The basement of the house, which was built in 1890 and renovated in 1956, is not finished.
How did their years of captivity go unnoticed?
Looking back on it, would police or neighbors done anything differently to increase the chances of discovering the imprisoned women?
And was Monday's escape by Berry the first time in a decade that any of the women had been able to signal anyone in the neighborhood about their plight?
Some neighbors of Ariel Castro have second-guessed themselves, asking if they could have prevented the horrors had they noticed details that now seem out of place.
For example, neighbor Daniel Marti -- who has described Castro as an "outgoing person, very nice guy" -- asked why he didn't question why the single man frequently carried bags full of McDonald's food into the house where he appeared to live alone, or why he frequently steered conversation away from it.
"Now that I think of it, he didn't want nobody back there," said Marti, who said he has known Ariel Castro since junior high school and lived near him for some 22 years.
Neighbors Israel Lugo and Nina Samoylicz told CNN that they had called police in recent years to report separate incidents at the home.
Samoylicz said she and others saw a naked woman in the home and called police.
Faliceonna Lopez, Samoylicz's sister, told a different version Tuesday night on CNN's "Piers Morgan Live." She said after seeing the woman, they told their mother, not police.
The mother, Annita Lugo, told Morgan that she didn't call police, either.
Another neighbor, Israel Lugo -- Annita Lugo's brother -- says he called police in 2011 when he heard yelling in the Castro home. Officers left when no one answered the door, Lugo says.